Prostate cancer
is often first detected through symptoms such as pain, difficulty
in urinating, and erectile dysfunction.
According to numerous studies, more than half of all men over 50
years of age suffer from an enlarged prostate and its symptoms.
As men age, up to 80% will suffer from uncomfortable symptoms that
may include difficulty urinating, increased frequency and urgency
of urination, bouts with sleep-disturbing nighttime urination and
painful lower backache.
Many men who develop prostate cancer never have any symptoms, undergo
no therapy, and eventually die of other causes.
Diagnosing prostate cancer is typically a three part protocol.
Part One - Prostate cancer is most often first
discovered by physical examination or by screening blood tests,
such as the PSA (prostate specific antigen) test.
NOTE: PSA tests can vary significantly day to day and can skyrocket
with other illnesses such as flu. In addition, false positives can
lead to unnecessary emotional distress.
Part two - Suspected prostate cancer is typically
confirmed by removing a piece of the prostate (biopsy) using a 10
needle prong, and examining it under a microscope. Many men have
absolutely no discomfort at all following this procedure. Others
may experience higher degrees of localised pain for a short period
following.
Part three - If a prostate biopsy indicates cancer
cells, MRI scans may be performed to determine whether prostate
cancer has spread. This is important in determing the best treatment
protocol.
Video - Prostate Cancer & PSA Tests
A discussion on psa tests and new drug Provenge used for treatment
of prostate cancer. [7:50] This video also includes other cancer
diagnosis and treatments other than prostate cancer.
PSA
The Prostate Specific Androgen score rises with
age. A normal upper limit for each age is [ng/mL]:
Age 40 to 49 - 2.5
Age 50 to 59 - 3.6
Age 60 to 69 - 4.5
Age 70 to 79 - 6.5
When your PSA levels are climbing to levels above this normal range,
then further tests are indicated.
The PSA level indicates how large and aggressive the prostate cancer
is. Not all men with prostate cancer need immediate treatment. Often
a watch and wait protocol will be established, but some patients
find this distressing and warrant earlier treatment options.
Following a radical prostatectomy, a patient can expect the PSA
level to fall to around 0.6 ng/mL rather quickly, and then to a
level of around 0.1 ng/mL
Gleason Score
The Gleason score provides an indication of the aggresiveness of
the cancer.
Score 2-4- indicates a slow growing cancer and
is curable by local treatment
Score of 5-7 - is growing moderately but is still
controllable
Score 8-10 - are growing rapidly and spreading
throughout the body
Gleason 6 can have a cancer doubling rate of around 6 years, whereas
a Gleason score of 10 can have a doubling time of only a month or
less.
Cancers that double quickly need rapid, aggressive treatment.
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